Salivary hormone testing (adrenal cortex) looks at the cumulative effects of stress that cause disruption of the natural rhythms and balancing mechanisms of steroid hormones thereby compromising sex hormones, neurotransmitter production and overall health. Closely evaluating the function of the adrenal glands is imperative in understanding the effects of stress. Salivary testing gives insight into the bioavailability of the unbound (free) hormones that are analyzed to capture circadian/luteal fluctuations.

Urine metabolic pathways and amino acid precursor testing evaluates (adrenal medulla) allowing for customized supplementation. Understanding brain chemistry plays in integral role in developing a full spectrum protocol. Energy, mood, sleep, and hormonal imbalances are direct results of stress. Whether physical or emotional, STRESS is the #1 issue effecting your body. Together they offer a dynamic and precise profile that serum testing alone cannot provide.

Functional endocrinology is the practice of looking at the body’s neuroendocrine hormonal systems through a root-cause, systems-based lens rather than just focusing on single hormone levels in isolation. Instead of only correcting numbers on a lab test, it explores why the endocrine system is imbalanced—considering stress, gut health, nutrient status, detox pathways, circadian rhythm, and lifestyle patterns.

It views hormones as part of a dynamic network, influenced by communication between the brain, adrenals, thyroid, ovaries/testes, pancreas, and even the gut microbiome. The goal isn’t simply replacement or suppression—it’s restoring balance and resiliency by optimizing how the body regulates and produces its own hormones.

In short:

Conventional endocrinology = “what are the numbers, how do we normalize them?”

Functional endocrinology = “why are these numbers out of balance, and how can we restore the body’s natural ability to self-regulate?”

Liposomal transdermal creams use advanced delivery technology where nutrients or hormones are wrapped in tiny protective “bubbles” made of healthy fats called liposomes. Because these liposomes resemble your body’s own cell membranes, they are much easier for your body to recognize and absorb. This means more of the active ingredient actually reaches your bloodstream and cells, instead of being lost in digestion or broken down too quickly. Liposomal delivery also provides a gentler, steadier release—helping you feel more balanced without the spikes or crashes that can happen with other methods. In functional endocrinology, this makes liposomal creams a powerful alternative to oral supplements or hormone therapies, since they are highly effective without stressing the gut or liver, and less invasive than injections or pellets. Formulations can be microgram-precise and bio-individualized.

Metabonomics is the science of studying how your body’s metabolism is working in real time—essentially, it looks at the unique chemical fingerprints your body produces as it processes nutrients, hormones, and toxins. By analyzing these patterns, we can see where your system may be under stress, out of balance, or in need of extra support.

When we use metabonomics to guide formulation, it means your cream isn’t made with a one-size-fits-all approach. Instead, it’s tailored to match your body’s specific needs and how your metabolism is actually functioning. This allows for a more precise, effective, and personalized therapy—helping restore balance and support your body’s natural ability to regulate hormones and heal.

The DUTCH test (Dried Urine Test for Comprehensive Hormones) is a widely used tool for assessing hormone health. It measures sex hormones (like estrogen, progesterone, testosterone), adrenal hormones (like cortisol and DHEA), and their metabolites through dried urine samples collected at specific times of the day. This helps map out hormone levels and patterns, especially adrenal rhythm and how your body processes estrogens. It’s a valuable test for spotting imbalances and giving a snapshot of hormone activity.

What makes our approach different is that we go beyond just measuring hormone levels. We use metabonomics, which looks at your body’s real-time metabolic activity—the unique chemical “fingerprints” your body produces as it processes hormones, nutrients, and toxins. Instead of simply seeing what hormone levels are present, metabonomics shows us why your hormones may be out of balance and how your metabolism is functioning as a whole.

From there, we formulate personalized liposomal transdermal creams, designed to support your body with exactly what it needs, in a form it can easily absorb and use. In short: DUTCH gives valuable hormone data, but our approach combines deeper metabolic insight with targeted therapy—offering both the information and the customized solution in one.

Regenerations is about Restoral! Our formulations include both precursors — plant-based compounds that “teach” your body to regenerate its own hormones naturally -- as well as microgram precise and bio-individualized compounds to provide immediate relief.

Why should one be concerned with hormone levels?

Hormones are your body’s chemical messengers—they control energy, mood, sleep, weight, focus, and even how well you handle stress. When hormones fall out of balance, it can show up as fatigue, brain fog, irritability, anxiety, sleep issues, weight gain, or low libido.

Left unaddressed, hormone imbalances can also contribute to long-term health concerns like thyroid issues, cardiovascular problems, insulin resistance, or bone loss. The good news is, when your hormones are supported properly, your body has the ability to restore balance and vitality—naturally.